Resistance of bovine colostral anti-cholera toxin antibody to in vitro and in vivo proteolysis.
AUTOR(ES)
McClead, R E
RESUMO
Pregnant cows immunized with cholera enterotoxin produce an immunoglobulin G class 1 antibody that enters the colostrum in high titer. After exposure to intestinal enzymes, this antibody remains immunologically reactive and inhibits intestinal fluid secretion in infant and adult rabbits exposed to cholera enterotoxin. Specific bovine colostral antibodies may be a source of passive immune protection for human infants and adults at risk for cholera and other enteric diseases.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=263544Documentos Relacionados
- Analysis of the roles of antilipopolysaccharide and anti-cholera toxin immunoglobulin A (IgA) antibodies in protection against Vibrio cholerae and cholera toxin by use of monoclonal IgA antibodies in vivo.
- Antigenic Specificity of Neutralizing Antibody to Cholera Toxin
- In Vitro Detection of Antibody to Cholera Enterotoxin in Cholera Patients and Laboratory Animals
- Inhibition by cholera toxin of rat polymorphonuclear leukocyte chemotaxis demonstrated in vitro and in vivo.
- Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis.