Restriction analysis and homology studies of the bovine adenovirus 7 genome.

AUTOR(ES)

Hu, S L

RESUMO

We located the cleavage sites for restriction endonucleases EcoRI, HindIII, and BamHI on the genome of bovine adenovirus 7. Cross-hybridization at reduced stringency revealed two regions of homology shared by the DNA of human adenovirus 2 and bovine adenoviruses 7 and 3. These regions correspond to the hexon and the IVa2 protein genes of the human adenovirus. Another region of homology shared only by the human adenovirus and bovine adenovirus 7 corresponded to the penton or the polypeptide IIIa genes. These results allowed us to align the restriction map of bovine adenovirus 7 with respect to the other adenoviruses.

Documentos Relacionados

• Bovine coronavirus genome.
• Integration of bovine leukemia virus DNA in the bovine genome.
• Nucleic acid homology studies of adenovirus type 7-SV40 interactions.
• The nucleotide sequence and restriction enzyme sites of the polyoma genome.
• Studies of adenovirus-SV40 hybrid viruses. IV. An adenovirus type 2 strain carrying the infectious SV40 genome.