Retinal horizontal cells: challenging paradigms of neural development and cancer biology

AUTOR(ES)

Poché, Ross A.

FONTE

Company of Biologists

RESUMO

A group of retinal interneurons known as horizontal cells has recently been shown to exhibit a variety of unique biological properties, as compared with other nerve cells, that challenge many long-standing assumptions in the fields of neural development and cancer biology. These features include their unusual migratory behavior, their unique morphological plasticity, and their propensity to divide at a relatively late stage during development. Here, we review these novel features, discuss their relevance for other cell types, outline open questions in our understanding of horizontal cell development and consider their implications.

Documentos Relacionados

• Effects of gamma-aminobutyric acid on skate retinal horizontal cells: evidence for an electrogenic uptake mechanism.
• Feedforward lateral inhibition in retinal bipolar cells: input-output relation of the horizontal cell-depolarizing bipolar cell synapse.
• Molecular biology of retinal ganglion cells.
• Monoclonal antibodies distinguish subtypes of retinal horizontal cells.
• When bugs meet cells: Conference: Frontiers of cellular microbiology and cell biology