Reversal of simian virus 40 small-t-antigen-induced theophylline resistance.

AUTOR(ES)
RESUMO

Simian virus 40 small-t antigen allows the growth of CV-1 cells in concentrations of theophylline that normally prevent cell cycling. This effect is completely overcome by two ionophores that uncouple mitochondria and by the anti-mitochondrial drug methylglyoxal bis-(guanylhydrazone).

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