RNA-Dependent RNA Polymerase Activity Associated with Virions and Subviral Particles of Myxoviruses
AUTOR(ES)
Chow, Nang-Ly
RESUMO
In vitro RNA synthesis is catalyzed by an enzyme found in purified virions of each of nine influenza strains tested. The extent of [3H]UTP incorporation observed is strain dependent, with an obligate requirement for Mn2+ ions and RNA template. At least 30% of purified product RNA shows resistance to degradation by ribonuclease A and T1 before and after annealing with exogenous RNA from influenza virions.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=389035Documentos Relacionados
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