SELECTIVE AND REVERSIBLE INHIBITION OF THE SYNTHESIS OF BACTERIAL DEOXYRIBONUCLEIC ACID BY PHENETHYL ALCOHOL

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Berrah, Ghoulem (Indiana University, Bloomington) and Walter A. Konetzka. Selective and reversible inhibition of the synthesis of bacterial deoxyribonucleic acid by phenethyl alcohol. J. Bacteriol. 83:738–744. 1962.—The selective inhibitory effects of phenethyl alcohol on gram-negative bacteria were confirmed with a variety of species. At a concentration of 0.25%, phenethyl alcohol was bacteriostatic for gram-negative bacteria; gram-positive cells were unaffected. Pseudomonas fluorescens required higher concentrations of the compound for inhibition than did the other gram-negative bacteria, and the gram-positive, acid-fast mycobacteria resembled the majority of gram-negative bacteria in sensitivity.

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