Selective imipenem resistance in Pseudomonas aeruginosa associated with diminished outer membrane permeability.
AUTOR(ES)
Studemeister, A E
RESUMO
The permeability of the outer membranes of imipenem-susceptible and imipenem-resistant clinical isolates of Pseudomonas aeruginosa was investigated by the liposome swelling assay. Sugars and cephaloridine penetrated rapidly, whereas imipenem penetrated poorly into liposomes constructed from porin-rich outer membrane fractions of the resistant isolates.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=172390Documentos Relacionados
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