Selective inactivation of the 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by heat.

AUTOR(ES)
RESUMO

Heat selectively inactivates the 3' to 5' exonuclease activity of E. coli DNA polymerase I, resulting in reduced dNTP turnover and lower fidelity of replication of homopolymer and natural DNA templates.

Documentos Relacionados