Sequence variation and methylation of the flax 5S RNA genes.
AUTOR(ES)
Goldsbrough, P B
RESUMO
The complete sequence of the flax 5S DNA repeat is presented. Length heterogeneity is the consequence of the presence or absence of a single direct repeat and the majority of single base changes are transition mutations. No sequence variation has been found in the coding sequence. The extent of methylation of cytosines has been measured at one location in the gene and one in the spacer. The relationship between the observed sequence heterogeneity and the level of methylation is discussed in the context of the operation of a correction mechanism.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=321107Documentos Relacionados
- Organisation of the 5S RNA genes in flax.
- Characterization of human 5S rRNA genes.
- Chromatin directed transcription of 5S and tRNA genes.
- Concerted evolution of dispersed Neurospora crassa 5S RNA genes: pattern of sequence conservation between allelic and nonallelic genes.
- Differential order of replication of Xenopus laevis 5S RNA genes.