Sequences in human cytomegalovirus which hybridize with the avian retrovirus oncogene v-myc are G + C rich and do not hybridize with the human c-myc gene.
AUTOR(ES)
Rasmussen, R D
RESUMO
The degree of relatedness between previously identified cross-hybridizing regions within human cytomegalovirus strain AD169 and the avian retrovirus oncogene v-myc were investigated by nucleotide sequence comparison. We found that the homologous regions between the human cytomegalovirus genome and v-myc are limited to short G + C-rich regions in each genome and that the human cytomegalovirus genome shares little or no homology with the human c-myc gene.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=366886Documentos Relacionados
- Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29.
- Human cytomegalovirus (strain AD169) contains sequences related to the avian retrovirus oncogene v-myc.
- FH3, a v-myc avian retrovirus with limited transforming ability.
- Biological activities of v-myc and rearranged c-myc oncogenes in rat fibroblast cells in culture.
- Heart tumors specifically induced in young avian embryos by the v-myc oncogene.
