Sequencing and analysis of four new Enterobacter ampD Alleles.
AUTOR(ES)
Ehrhardt, A F
RESUMO
Sequences of ampD genes from wild-type, temperature-sensitive, and stably derepressed mutants of the wild-type strain of Enterobacter cloacae 029 and the hyperinducible strain E. cloacae 1194E were determined and compared with the ampD gene of the wild-type strain E. cloacae 14. Seventy nucleotide differences were found between the wild-type sequences, resulting in 13 amino acid changes. The deduced amino acid changes do not correspond to published AmpC regulation mutations and expand the number of known mutations leading to altered AmpC beta-lactamase expression in members of the family Enterobacteriaceae.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=163450Documentos Relacionados
- Altered phenotypes associated with ampD mutations in Enterobacter cloacae.
- Sequences of wild-type and mutant ampD genes of Citrobacter freundii and Enterobacter cloacae.
- AmpD Is Required for Regulation of Expression of NmcA, a Carbapenem-Hydrolyzing β-Lactamase of Enterobacter cloacae
- DNA sequence differences of ampD mutants of Citrobacter freundii.
- An ampD Gene in Pseudomonas aeruginosa Encodes a Negative Regulator of AmpC β-Lactamase Expression
