Single channel currents induced by complement in antibody-coated cell membranes.
AUTOR(ES)
Jackson, M B
RESUMO
An extracellular patch electrode was used to record ionic currents from individual complement-induced channels in the membranes of antibody-coated skeletal muscle. The amplitude of the single-channel currents leads to an estimate of 90 pS for the unit conductance. The kinetics of channel opening and closing show marked variability and complexity. Channels flicker open and closed repeatedly, indicating that once these lesions form, they undergo rapid structural transitions between discrete conducting and nonconducting states.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=349051Documentos Relacionados
- Human Rotavirus Detection by Agglutination of Antibody-Coated Erythrocytes
- Enzyme immunoassay for detection of antibody-coated bacteria.
- Detection of rotavirus by serological trapping on antibody-coated electron microscope grids.
- Slide method for detection of antibody-coated bacteria in urine sediments.
- Reproducibility of interpretation of the test for antibody-coated bacteria in urinary sediment.