Sodium- and potassium-activated ATPase. A possible target of aldosterone.
AUTOR(ES)
Schmidt, U
RESUMO
Na-K-ATPase activity was measured with an ultramicromethod in single portions of the proximal and distal convolution and of the thick ascending limb of Henle from adrenalectomized rats and after treatment with 5 mug aldosterone per 100 g body wt. The activity in all tubular structures returned to normal within 1 h after injection. This rapid activation of Na-K-ATPase induced by hormone was completely prevented by actinomycin D and cycloheximide. It appears that this aldosterone effect on Na-K-ATPase requires an intact protein synthetic process.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=301794Documentos Relacionados
- Aldosterone Action and Sodium- and Potassium-Activated Adenosine Triphosphatase in Toad Bladder
- Stable gene amplification and overexpression of sodium- and potassium-activated ATPase in HeLa cells.
- Renal Sodium- and Potassium-Activated Adenosine Triphosphatase and Sodium Reabsorption in the Hypothyroid Rat
- SODIUM-POTASSIUM-ACTIVATED ATPase AND POTASSIUM-ACTIVATED p-NITROPHENYLPHOSPHATASE: A COMPARISON OF THEIR SUBCELLULAR LOCALIZATIONS IN RAT BRAIN*
- Stimulation of hepatic sodium and potassium-activated adenosine triphosphatase activity by phenobarbital. Its possible role in regulation of bile flow.