Some repair-deficient mutants of Dictyostelium discoideum display enhanced susceptibilities to bleomycin.
AUTOR(ES)
Deering, R A
RESUMO
Dictyostelium discoideum, a soil eukaryote, is highly resistant to DNA-damaging agents; repair mutants are more susceptible. Susceptibility to bleomycin, produced by Streptomyces verticillus, is greater for mutants which are susceptible to other agents than for resistant strains. The high potential for DNA repair may result from the need to cope with chemicals produced by other soil microorganisms.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=163135Documentos Relacionados
- Lack of Chemically Induced Mutation in Repair-Deficient Mutants of Yeast
- Altered spectra of hypermutation in DNA repair-deficient mice.
- Meiotic Recombination and Sporulation in Repair-Deficient Strains of Yeast
- Toxicity of organic acids for repair-deficient strains of Escherichia coli.
- Toxicity of Irradiated Medium for Repair-Deficient Strains of Escherichia coli