Stable Equilibria at Two Loci in Populations with Large Selfing Rates
AUTOR(ES)
Hastings, Alan
RESUMO
The equilibrium structure of two-locus, two-allele models with very large selfing rates is found using perturbation techniques. For free recombination, r = ½, the following results hold. If the heterozygotes do not have at least an approximate 30% advantage in fitness relative to homozygotes, a stable equilibrium with all alleles present is possible only if all of the homozygote fitnesses differ at most by approximately the outcrossing rate, t, and all stable polymorphic equilibria have disequilibrium values, D, that are at most on the order of the outcrossing rate. Once the heterozygote fitnesses are above the threshold, there are stable equilibria possible with D near its maximum possible value. The results show that the observed disequilibria in highly selfed plant populations are not likely to result from selection leading to an equilibrium.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1202478Documentos Relacionados
- Four Simultaneously Stable Polymorphic Equilibria in Two-Locus Two-Allele Models
- Population Dynamics Inferred from Temporal Variation at Microsatellite Loci in the Selfing Snail Bulinus Truncatus
- Spontaneous mutation rates at enzyme loci in Drosophila melanogaster.
- Molecular clock rates at loci under stabilizing selection.
- Loci Differentially Affected by Selection in Two American Black Populations*