Stimulation of Rabies Vaccine in Mice by Low Doses of Polyadenylic: Polyuridylic Complex
AUTOR(ES)
Branche, Robert
RESUMO
Addition of 100 μg of polyadenylic: polyuridylic (poly A:U) complex to each dose of inactivated rabies vaccine increased immunity to rabies challenge in mice. Stimulation was also observed after addition of 10 μg of poly A:U to the vaccines. Mixtures of rabies vaccine and poly A:U lost their stimulatory properties after storage at 37 or 4 C for 1 month. However, these data are encouraging for practical use of poly A:U as an adjuvant to viral vaccines.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=422534Documentos Relacionados
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