Synergistic Effect of Herpes Simplex Virus and Cytosine Arabinoside on Human Chromosomes
AUTOR(ES)
O'Neill, F. J.
RESUMO
The combined treatment of cultures of human embryonic lung cells with herpes simplex virus type 2 and cytosine arabinoside produced a significantly increased number of cells containing multiple chromatid and chromosome breaks. The incidence of such cells was found to be approximately two and one half times greater than the additive effects of virus and cytosine arabinoside induced separately and is therefore synergistic.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=356183Documentos Relacionados
- Effect of cytosine arabinoside on viral-specific protein synthesis in cells infected with herpes simplex virus.
- Synergistic effect of human leukocyte interferon and nonoxynol 9 against herpes simplex virus type 2.
- Cytosine Arabinoside Therapy for Herpes Simplex Encephalitis—Clinical Experience with Six Patients
- Effect of uracil arabinoside on metabolism and cytotoxicity of cytosine arabinoside in L5178Y murine leukemia.
- Effect of Cytosine Arabinoside, Adenine Arabinoside, Tilorone, and Rifamycin SV on Multiplication of Herpesvirus saimiri In Vitro