Synthesis of (3'-5'),(2'-5')-linked di- and tri-adenylyl methylphosphonate analogs.
AUTOR(ES)
Wang, C G
RESUMO
Stereoselectivity was found during the coupling reaction, to form 2',5'- and 3',5'-linked di- and triadenylyl methylphosphonate. The configuration of phosphorus was determined by 1HNMR NOE.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=309762Documentos Relacionados
- H3 lysine 4 di- and tri-methylation deposited by cryptic transcription attenuates promoter activation
- Antiherpesvirus activity and mechanism of action of indolo-(2,3-b)quinoxaline and analogs.
- Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs.
- Chemical synthesis and biological characterization of phosphorothioate analogs of 2', 5'-3'-deoxyadenylate trimer.
- A new approach to the synthesis of the 5'-deoxy-5'-methylphosphonate linked thymidine oligonucleotide analogues.