Synthesis of opiate peptides by a clonal pituitary tumor cell line.
AUTOR(ES)
Giagnoni, G
RESUMO
Clonal mouse pituitary tumor cells, AtT-20, synthesize at least four species of peptides with opiate activity. The endorphin concentration of AtT-20 cells was estimated to be 300-600 pmol/mg of protein. The two most abundant endorphins with apparent molecular weights of 1800 and 2400 were purified 300- and 24-fold, respectively; additional minor components were found with apparent molecular weights of greater than 3000 and less than 750.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=432149Documentos Relacionados
- Storage and release of acetylcholine by a clonal cell line.
- Synthesis of low molecular weight heat shock peptides stimulated by ecdysterone in a cultured Drosophila cell line.
- Elimination of potassium channel expression by antisense oligonucleotides in a pituitary cell line.
- Substance P enhances cholinergic receptor desensitization in a clonal nerve cell line.
- Nerve growth factor-mediated induction of tyrosine hydroxylase in a clonal pheochromocytoma cell line.