The Capsule of Bacillus anthracis Behaves as a Thymus-Independent Type 2 Antigen
AUTOR(ES)
Wang, Taia T.
FONTE
American Society for Microbiology
RESUMO
Bacillus anthracis elaborates a homopolymeric capsule composed of γ-d-glutamic acid residues. Mice were immunized with formalin-fixed encapsulated B. anthracis bacilli, and the serum antibody response to a γ-d-glutamyl capsular epitope was measured. Antiglutamyl antibodies were elicited in athymic BALB/c Nu/Nu, BALB/c Nu/+, and CBA/J mice but not in CBA/N xid mice. These response patterns define the capsule of B. anthracis as a thymus-independent type 2 antigen.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=517462Documentos Relacionados
- Ia-antigen-T-cell interactions for a thymus-independent antigen composed of D amino acids.
- Primary antibody responses to thymus-independent antigens in the lungs and hilar lymph nodes of mice.
- Immunoglobulin D-deficient mice can mount normal immune responses to thymus-independent and -dependent antigens.
- Evidence of Thymus-Independent Local and Systemic Antibody Responses to Cryptosporidium parvum Infection in Nude Mice
- Rise in Inulin-Sensitive B Cells During Ontogeny Can Be Prematurely Stimulated by Thymus-Dependent and Thymus-Independent Antigens
