The Intact Retroviral Env Glycoprotein of Human Foamy Virus Is a Trimer

AUTOR(ES)

Wilk, Thomas

FONTE

American Society for Microbiology

RESUMO

Electron microscopy of negatively stained human foamy virus particles provides direct evidence for the trimeric nature of intact Env surface glycoproteins. Three-dimensional image reconstruction reveals that the Env trimer is a tapering spike 14 nm in length. The spikes were often arranged in hexagonal rings which shared adjacent Env trimers.

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