The location of the globin mRNA sequence within its 16S precursor.

AUTOR(ES)

Smith, K

RESUMO

The coding sequence of globin mRNA has been located at or very close to the 3' end of its poly(A)-containing 16S precursor. The 16S RNA was annealed to globin cDNA and the hybrid digested with ribonuclease H. The undigested fragment did not bind to oligo(dT)-cellulose and its size was that expected for the intact 5' portion of the precursor.

Documentos Relacionados

• Sequence organization of the beta-globin mRNA precursor.
• The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor.
• Non-random localization of ribonucleoprotein (RNP) structures within an adenovirus mRNA precursor.
• The number of ribosomes on simian virus 40 late 16S mRNA is determined in part by the nucleotide sequence of its leader.
• Mutational alterations within the simian virus 40 leader segment generate altered 16S and 19S mRNA's.