The major role of Spo0A in genetic competence is to downregulate abrB, an essential competence gene.
AUTOR(ES)
Hahn, J
RESUMO
We show that the major role for Spo0A in the development of genetic competence is to downregulate expression of abrB. AbrB is both a negative regulator and a positive regulator of competence. The negative effects are exerted at multiple points in competence regulation. A regulatory mechanism that is independent of mecA and abrB operates on comK expression.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=177070Documentos Relacionados
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