The MAP2/Tau family of microtubule-associated proteins

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FONTE

BioMed Central

RESUMO

Microtubule-associated proteins (MAPs) of the MAP2/Tau family include the vertebrate proteins MAP2, MAP4, and Tau and homologs in other animals. They are best known for their microtubule-stabilizing activity roles regulating microtubule networks but, accumulating evidence suggests a much broader range of functions. regulation of microtubule-mediated transport. Tau is also implicated in Alzheimer’s disease and other dementias.

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