THE MECHANISM OF VIRAL CARCINOGENESIS BY DNA MAMMALIAN VIRUSES, VI. A NEW CLASS OF VIRUS-SPECIFIC RNA MOLECULES IN CELLS TRANSFORMED BY GROUP C HUMAN ADENOVIRUSES*

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RESUMO

A new class of virus-specific RNA molecules was found in cells transformed by group C human adenovirus types 2, 5, and 6. RNA isolated from virus-free rat embryo cells transformed by adenovirus 2, 5, and 6 hybridized with all group C adenovirus DNA's (adenovirus 1, 2, 5, and 6) equally well, but not appreciably with group A and B adenovirus DNA's. Most likely no viral genes common to group A, B, and C adenoviruses are transcribed in adenovirus-transformed cells.

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