The Na/K pump, Cl ion, and osmotic stabilization of cells

AUTOR(ES)
FONTE

The National Academy of Sciences

RESUMO

An equation for membrane voltage is derived that takes into account the electrogenicity of the Na/K pump and is valid dynamically, as well as in the steady state. This equation is incorporated into a model for the osmotic stabilization of cells. The results emphasize the role of the pump and membrane voltage in lowering internal Cl− concentration, thus making osmotic room for vital substances that must be sequestered in the cell.

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