The neural cell adhesion molecule L1 is distinct from the N-CAM related group of surface antigens BSP-2 and D2.
AUTOR(ES)
Faissner, A
RESUMO
The neural cell adhesion molecule L1 and the group of N-CAM related molecules, BSP-2 and D2 antigen, are immunochemically distinct molecular species. The two groups of surface molecules are also functionally distinct entities, since inhibition of Ca2+-independent adhesion among early post-natal mouse cerebellar cells by Fab fragments of both antibodies are at least additive, when compared with equal concentrations of the individual antibodies.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=557418Documentos Relacionados
- Characterization of the cell adhesion molecules L1, N-CAM and J1 in the mouse intestine.
- Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM
- Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM
- Cell adhesion molecule N-CAM is expressed by denervated myofibres in Werdnig-Hoffman and Kugelberg-Welander type spinal muscular atrophies.
- Neural cell adhesion molecule (N-CAM) accumulates in denervated and paralyzed skeletal muscles.