The nucleotide sequence coding for major outer membrane protein OmpA of Shigella dysenteriae.
AUTOR(ES)
Braun, G
RESUMO
The nucleotide sequence of the ompA gene from Shigella dysenteriae has been determined and the amino acid sequence of the pro-OmpA protein predicted. Sequence comparison between the ompA genes of S.dysenteriae and Escherichia coli showed that features such as mRNA secondary structure and codon usage, as well as polypeptide function, have been conserved during evolution. The pro-OmpA protein of S.dysenteriae consists of 351 residues, as opposed to the 346 of the E.coli protein and also shows several amino acid changes. These changes have been used to interpret differences in the biological activity of the two proteins.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=320615Documentos Relacionados
- Nucleotide sequence of the gene ompA coding the outer membrane protein II of Escherichia coli K-12.
- Cloning and expression in Escherichia coli K-12 of the genes for major outer membrane protein OmpA from Shigella dysenteriae, Enterobacter aerogenes, and Serratia marcescens.
- Regulatory region of the gene for the ompA protein, a major outer membrane protein of Escherichia coli
- The major outer membrane protein of Haemophilus ducreyi consists of two OmpA homologs.
- Involvement of a 43-kilodalton outer membrane protein in beta-lactam resistance of Shigella dysenteriae.