The Polar Flagellar Motor of Vibrio cholerae Is Driven by an Na+ Motive Force

AUTOR(ES)

Kojima, Seiji

FONTE

American Society for Microbiology

RESUMO

Vibrio cholerae is a highly motile bacterium which possesses a single polar flagellum as a locomotion organelle. Motility is thought to be an important factor for the virulence of V. cholerae. The genome sequencing project of this organism is in progress, and the genes that are highly homologous to the essential genes of the Na+-driven polar flagellar motor of Vibrio alginolyticus were found in the genome database of V. cholerae. The energy source of its flagellar motor was investigated. We examined the Na+ dependence and the sensitivity to the Na+ motor-specific inhibitor of the motility of the V. cholerae strains and present the evidence that the polar flagellar motor of V. cholerae is driven by an Na+ motive force.

Documentos Relacionados

• Requirements for Conversion of the Na+-Driven Flagellar Motor of Vibrio cholerae to the H+-Driven Motor of Escherichia coli
• The Sodium-Driven Flagellar Motor Controls Exopolysaccharide Expression in Vibrio cholerae
• Sucrose uptake is driven by the Na+ electrochemical potential in the marine bacterium Vibrio alginolyticus.
• Characterization of the Bacillus subtilis motile system driven by an artificially created proton motive force.
• Hybrid Motor with H+- and Na+-Driven Components Can Rotate Vibrio Polar Flagella by Using Sodium Ions