The Salmonella typhimurium LT2 uvrD gene is regulated by the lexA gene product.
AUTOR(ES)
Pang, P P
RESUMO
The uvrD gene product apparently plays a role in the repair of UV damage, in mismatch repair, and in genetic recombination. A lower level of expression of the Salmonella typhimurium LT2 uvrD gene was observed in maxicells prepared from an Escherichia coli strain that contained a lexA+ plasmid than in maxicells prepared from an E. coli strain that lacked functional LexA protein. These results suggest that the uvrD+ gene is repressed by the LexA protein and is thus a member of the set of genes whose expression is increased by "SOS"-inducing treatments.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=217635Documentos Relacionados
- Identification of the uvrD gene product of Salmonella typhimurium LT2.
- Sequence of the Salmonella typhimurium LT2 lexA gene and its regulatory region.
- Transcription of the uvrD gene of Escherichia coli is controlled by the lexA repressor and by attenuation.
- DNA repair in Escherichia coli: identification of the uvrD gene product.
- Mechanism of action of the lexA gene product.
