The Virion Host Shutoff Protein of Herpes Simplex Virus Type 1 Has RNA Degradation Activity in Primary Neurons
AUTOR(ES)
Strand, Stephanie S.
FONTE
American Society for Microbiology
RESUMO
The virion host shutoff protein (Vhs) of herpes simplex virus type 1 induces destabilization of mRNA following infection. Our study of primary neurons from CD-1 mice demonstrates that vhs is functional in neurons but that more Vhs is required to mediate RNA degradation in neurons than in other susceptible cells.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=446108Documentos Relacionados
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