Topical indomethacin effect on neovascularisation of the cornea and on prostaglandin E2 levels.
AUTOR(ES)
Frucht, J
RESUMO
The effect of indomethacin 1% drops against a placebo (NaCl 0.9% solution) was tested in rabbits' corneas injured by a standardized chemical burn. The corneas treated with indomethacin 1% had less neovascularisation and a much smaller increase in the PGE2 levels as compared with the control fellow eyes treated with a placebo. It appears that indomethacin 1% drops have a clear effect on the inflammatory response of the cornea and deserve a clinical trial in selected patients suffering from corneal inflammatory changes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1040434Documentos Relacionados
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