Transcription of DNA-histone complexes by yeast RNA polymerase B.
AUTOR(ES)
Karagyozov, L K
RESUMO
Transcription of denatured DNA complexed with histones (total, H1 or H2A/H2B/H3/H4) by yeast RNA polymerase B is investigated. Binding of histones to DNA restricts its template activity by decreasing the formation of active, heparin-resistant, RNA polymerase initiation complexes. The elongation of pre-initiated RNA on denatured DNA, complexed with histones, is possible, although resulting in somewhat shorter RNA chains. It is suggested that RNA polymerase B can elongate on a DNA strand covered with histones.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=342133Documentos Relacionados
- Structural investigations of DNA-histone complexes. A spin label study.
- DNA-histone interaction in the vicinity of replication points.
- Nucleosomal structure at hyperacetylated loci probed in nuclei by DNA-histone crosslinking.
- Acetylation of Histone H3 at the Nucleosome Dyad Alters DNA-Histone Binding*
- Histone-DNA interactions within chromatin. Isolation of histones from DNA-histone adducts induced in nuclei by UV light.
