Transient uptake of serotonin by newborn olfactory projection neurons
AUTOR(ES)
Beltz, Barbara S.
FONTE
The National Academy of Sciences
RESUMO
A life-long turnover of sensory and interneuronal populations has been documented in the olfactory pathways of both vertebrates and invertebrates, creating a situation where the axons of new afferent and interneuronal populations must insert into a highly specialized glomerular neuropil. A dense serotonergic innervation of the primary olfactory processing areas where these neurons synapse also is a consistent feature across species. Prior studies in lobsters have shown that serotonin promotes the branching of olfactory projection neurons. This paper presents evidence that serotonin also regulates the proliferation and survival of projection neurons in lobsters, and that the serotonergic effects are associated with a transient uptake of serotonin into newborn neurons.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=60122Documentos Relacionados
- Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb
- Transient projection from the superior temporal sulcus to area 17 in the newborn macaque monkey.
- THE PROJECTION OF THE OLFACTORY EPITHELIUM ON THE OLFACTORY BULB IN THE RABBIT
- Modulation of a transient K+ current in the pleural sensory neurons of Aplysia by serotonin and cAMP: implications for spike broadening.
- Differential loss of striatal projection neurons in Huntington disease.
