Translational Features of Human Alpha 2b Interferon Production in Escherichia coli
AUTOR(ES)
Valente, C. A.
FONTE
American Society for Microbiology
RESUMO
The yield of human alpha 2b interferon in Escherichia coli was optimized by replacement of low-usage arginine codons located in the mRNA 5′ end. The differences observed among the various gene variants suggest that codon usage, Shine-Dalgarno-like sequences, and mRNA secondary structure contribute to the performance of E. coli translation machinery.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=492429Documentos Relacionados
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