Two Novel Promoters in the Upstream Regulatory Region of Human Papillomavirus Type 31b Are Negatively Regulated by Epithelial Differentiation
AUTOR(ES)
Ozbun, Michelle A.
FONTE
American Society for Microbiology
RESUMO
Organotypic cultures support the stratification and differentiation of keratinocytes and the human papillomavirus (HPV) life cycle. We report transcription from four novel promoters in the HPV31b upstream regulatory region during the viral life cycle in organotypic cultures. Promoter initiation was not differentiation dependent; two promoters were down-regulated upon epithelial differentiation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=104120Documentos Relacionados
- Induction of the Upstream Regulatory Region of Human Papillomavirus Type 31 by Dexamethasone Is Differentiation Dependent
- Temporal Usage of Multiple Promoters during the Life Cycle of Human Papillomavirus Type 31b
- Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes.
- The Upstream Regulatory Region of Human Papillomavirus Type 31 Is Insensitive to Glucocorticoid Induction
- Human Papillomavirus Type 31b Infection of Human Keratinocytes and the Onset of Early Transcription
