Ubiquitous mammalian-wide interspersed repeats (MIRs) are molecular fossils from the mesozoic era.
AUTOR(ES)
Jurka, J
RESUMO
Short interspersed elements (SINEs) are ubiquitous in mammalian genomes. Remarkable variety of these repeats among placental orders indicates that most of them amplified in each lineage independently, following mammalian radiation. Here, we present an ancient family of repeats, whose sequence divergence and common occurrence among placental mammals, marsupials and monotremes indicate their amplification during the Mesozoic era. They are called MIRs for abundant Mammalian-wide Interspersed Repeats. With approximately 120,000 copies still detectable in the human genome (0.2-0.3% DNA), MIRs represent a 'fossilized' record of a major genetic event preceding the radiation of placental orders.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=306646Documentos Relacionados
- Large-scale analysis of exonized mammalian-wide interspersed repeats in primate genomes
- Ubiquitous, interspersed repeated sequences in mammalian genomes.
- Stereotaxic thalamotomy--experiences from the levodopa era.
- Morphological Interpretation of Reflectance Spectrum (MIRS) using libraries looking towards soil classification
- Tuberculosis in the AIDS era.