Uniparental Cytogamy: A Novel Method for Bringing Micronuclear Mutations of Tetrahymena into Homozygous Macronuclear Expression with Precocious Sexual Maturity

AUTOR(ES)

Cole, E. S.

RESUMO

A new method of inducing self-fertilization, uniparental cytogamy, yields homozygous germinal and somatic genotypes in the ciliate Tetrahymena thermophila. Progeny are highly fertile and show a marked tendency for precocious sexual maturity. This method is highly effective in protocols designed to generate and express nonlethal dominant or recessive mutations.

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