Use of trans-Sialidase Inhibition Assay in a Population Serologically Negative for Trypanosoma cruzi but at a High Risk of Infection
AUTOR(ES)
Leguizamón, María S.
FONTE
American Society for Microbiology
RESUMO
trans-Sialidase inhibition assay (TIA) was employed in a population at high risk of Trypanosoma cruzi infection. From 20 serum samples that were negative by conventional serologic and parasitologic assays, 18 (90%) were reactive in TIA, providing further evidence of the higher sensitivity of TIA and suggesting that the actual prevalence of T. cruzi infection might be underestimated.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=121368Documentos Relacionados
- Heterologous Expression of Trypanosoma cruzi trans-Sialidase in Leishmania major Enhances Virulence
- Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi.
- trans-Sialidase Inhibition Assay, a Highly Sensitive and Specific Diagnostic Test for Chagas' Disease
- Stage-specific expression and intracellular shedding of the cell surface trans-sialidase of Trypanosoma cruzi.
- Invasive phenotype of Trypanosoma cruzi restricted to a population expressing trans-sialidase.