Utilization of Palmitic Acid by Mycobacterium avium
AUTOR(ES)
McCarthy, Charlotte
RESUMO
Mycobacterium avium accumulates 14C-palmitic acid with saturation kinetics; the process is both temperature dependent and pH sensitive. The fatty acid is incorporated into triglyceride in vivo and the conversion is detectable within 5 min after exposure of the cells to 14C-palmitic acid. The triglyceride is rapidly utilized because 14CO2 evolution from it begins within 30 min after 14C-palmitic acid accumulation. Data from silicic acid column chromatography of extracts of cultures that have divided many times in medium containing 14C-palmitic acid indicate that a large proportion of the cell lipid is triglyceride, but the radioactivity is widely dispersed among the other lipids. It is estimated that about 5% of the cell dry weight is triglyceride in a postexponential culture.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=416288Documentos Relacionados
- Effect of Palmitic Acid Utilization on Cell Division in Mycobacterium avium
- Oxidation of palmitic acid by Mycobacterium leprae in an axenic medium.
- INTRACELLULAR CONJUGATION AND DETOXIFICATION OF PALMITIC ACID BY MYCOBACTERIUM TUBERCULOSIS1
- Utilization of nitrate or nitrite as single nitrogen source by Mycobacterium avium.
- Uric acid utilization by Mycobacterium intracellulare and Mycobacterium scrofulaceum isolates.