Vaccination with Purified Dr Fimbriae Reduces Mortality Associated with Chronic Urinary Tract Infection Due to Escherichia coli Bearing Dr Adhesin

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

The vaccination of C3H/HeJ mice with Escherichia coli Dr fimbrial antigen reduced mortality associated with an experimental urinary tract infection due to a homologous strain bearing Dr adhesin. Immune sera with high titers of anti-Dr antibody inhibited bacterial binding to bladders and kidneys but did not affect the rate of renal colonization.

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