Value of serological diagnosis in congenital syphilis. Report of nine cases.

AUTOR(ES)

Borobio, M V

RESUMO

The diagnosis of congenital syphilis is difficult since it depends mainly on the results of serological tests. The results of five serological tests (three specific and two non-specific) in nine neonates with congenital syphilis are compared with those obtained in three with passively acquired antibodies. It appeared that the serological diagnosis of congenital syphilis must be based on the finding of specific neonatal antibodies in cord serum, which give positive results to the fluorescent treponemal antibody absorption test for immunoglobulin M, together with high titres of total IgM and negative results to latex tests. The non-specific tests are useful for confirming the efficacy of treatment. The mean number of cases of congenital syphilis in Seville is 0.81/1000 live births.

Documentos Relacionados

• Hepatitis in early syphilis. Report of three cases.
• Analysis of western blotting (immunoblotting) technique in diagnosis of congenital syphilis.
• Complete congenital heart block. Report of 35 cases.
• Evaluation of immunoglobulin M western blot analysis in the diagnosis of congenital syphilis.
• Rheumatoid factor in congenital syphilis.