X-linked recessive type of pure spastic paraplegia in a large pedigree: absence of detectable linkage with Xg.
AUTOR(ES)
Zatz, M
RESUMO
A family with 24 males affected by an X-linked type of spastic paraplegia is reported. Twelve affected members were personally examined showing the pure form of the disease. Half of the affected males had many descendants, all normal. Linkage studies strongly suggest that this X-linked form of spastic paraplegia and Xg loci are not at a measurable distance on the X chromosome.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1013396Documentos Relacionados
- Progressive spastic paraplegia due to persistent echo virus encephalomyelitis in a child with X-linked hypogammaglobulinaemia.
- Genetic study of a new X-linked recessive immunodeficiency syndrome.
- X-linked recessive bulbospinal neuronopathy: a report of ten cases.
- A genetic linkage study of a kindred with X-linked retinitis pigmentosa.
- Mapping the gene causing X-linked recessive nephrolithiasis to Xp11.22 by linkage studies.