Yersinia associated arthritis in SHR rats: effect of the microbial status of the host.

AUTOR(ES)

Gripenberg-Lerche, C

RESUMO

Following the intravenous injection of live Yersinia enterocolitica O:8, 50-69% of SHR rats developed arthritis; these rats were antibody free against all rat pathogens tested. In contrast, only 20-25% of SHR rats which had serum antibodies against Bacillus piliformis, Kilham rat virus, and Toolan H-1 virus developed arthritis. The results indicate that the microbial load of the host has a profound effect on the susceptibility to experimental arthritis.

Documentos Relacionados

• Long term follow up of SHR rats with experimental yersinia associated arthritis.
• Role of host factors in the pathogenesis of Salmonella-associated arthritis in rats.
• Adenoviruses in the immunocompromised host.
• Immune responses in yersinia-associated reactive arthritis.
• Experimental Asbestosis in Rats: The Effect of Particle Size and of Added Alumina