Yop Fusions to Tightly Folded Protein Domains and Their Effects on Yersinia enterocolitica Type III Secretion
AUTOR(ES)
Lee, Vincent T.
FONTE
American Society for Microbiology
RESUMO
Yersinia enterocolitica organisms secrete Yop proteins via the type III pathway. Translational fusion of yop genes to ubiquitin or dihydrofolate reductase results in hybrid proteins that cannot be secreted. The folding of hybrids prevents their own transport, but it does not hinder the type III secretion of other Yops.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=135149Documentos Relacionados
- Yersinia enterocolitica Type III Secretion: Mutational Analysis of the yopQ Secretion Signal
- The Secretion Signal of YopN, a Regulatory Protein of the Yersinia enterocolitica Type III Secretion Pathway†
- Yersinia enterocolitica type III secretion: Evidence for the ability to transport proteins that are folded prior to secretion
- Regulated Secretion of YopN by the Type III Machinery of Yersinia enterocolitica
- A Synonymous Mutation in Yersinia enterocolitica yopE Affects the Function of the YopE Type III Secretion Signal