Basement Membrane Pathology
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Dimensões das vias aéreas na asma fatal e na doença pulmonar obstrutiva grave / Airway dimensions in fatal asthma and severe COPD
Background: In some patients with chronic asthma, clinical and physiological similarities with chronic obstructive pulmonary disease may co-exist, such as partial reversibility to bronchodilators despite persistent expiratory airflow obstruction. However, pathologic analyses comparing both diseases in patients of similar age and disease severity are scarce.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/09/2011
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2. The extracellular matrix in multiple sclerosis: an update
Extracellular matrix (ECM) molecules play important roles in the pathobiology of the major human central nervous system (CNS) inflammatory/demyelinating disease multiple sclerosis (MS). This mini-review highlights some recent work on CNS endothelial cell interactions with vascular basement membrane ECM as part of the cellular immune response, and roles for w
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-05
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3. Morphological changes and pathology of mouse glomeruli infected with a streptococcal L-form or exposed to lipoteichoic acid.
The morphology and pathology of cultured mouse glomeruli were examined at the cellular and subcellular levels after infection with a physiological isotonic L-form of Streptococcus pyogenes type 12 or exposure to streptococcal lipoteichoic acid. These changes, as viewed by light microscopy, were identical regardless of the method used to induce glomerular cyt
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4. Passage of Salmonella enteritidis and Salmonella thompson through chick ileocecal mucosa.
The passage of Salmonella enteritidis and S. thompson across the cecal mucosa has been visualized in an electron microscope study with the freshly hatched chick as a model. The uptake of salmonellae by macrophages took place in the cecal lumen; the macrophages became abnormal and often ruptured to release organisms back into the lumen. The entry of bacteria
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5. Vasculitis and renal disease in nail-patella syndrome: case report and literature review.
A 57 year old man with nail-patella syndrome (NPS) and associated renal disease is described who developed an inflammatory polyarthropathy and polyarteritis-like vasculitis. Vasculitis and serum complement abnormalities have not previously been reported in NPS. NPS is a rare autosomal dominant connective tissue disorder affecting both mesenchymal and ectoder
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6. Quantitative histopathology can aid diagnosis in painful bladder syndrome.
AIMS: To define the pathology of painful bladder syndrome using a morphometric method. METHODS: Bladder biopsy specimens from 31 patients with painful bladder syndrome and 11 controls were stained and examined at x260 magnification with the aid of a 100 square counting grid. Random counts of the different tissues and inflammatory components were made to asce
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7. Immunoalkaline phosphatase technique applied to paraffin wax embedded tissues in diagnostic renal pathology.
An indirect immunoalkaline phosphatase (IAP) technique was used to evaluate the glomerular deposition of immunoglobulins, C3, C1q and fibrinogen. In 80 renal biopsy specimens the results obtained using this technique were compared with those obtained by direct immunofluorescence to see if it could be used as a viable alternative. The IAP technique was straig
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8. Some histological changes in chronic bronchitis and asthma
The differences in two groups of patients (24 with chronic bronchitis and 24 with bronchial asthma) were compared by bronchoscopy and bronchial biopsies. The same investigations were carried out on 24 healthy control subjects. The only bronchoscopic difference between the two groups was hypertonicity of the bronchial wall, which was frequent in the asthmatic
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9. Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes
Anti-C1q autoantibodies are present in sera of patients with several autoimmune diseases, including systemic lupus erythematosus (SLE). Strikingly, in SLE the presence of anti-C1q is associated with the occurrence of nephritis. We have generated mouse anti–mouse C1q mAb’s and used murine models to investigate whether anti-C1q autoantibodies actually cont
American Society for Clinical Investigation.