Beta 2 Adrenergic Receptors
Mostrando 1-12 de 202 artigos, teses e dissertações.
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1. Papel dos receptores beta 2-adrenérgicos nas alterações musculoesqueléticas desencadeadas pela insuficiência cardíaca. / Role of beta2-adrenergic receptors on skeletal muscle alterations induced by heart failure
A insuficiência cardíaca (IC) é uma síndrome complexa que envolve múltiplos sistemas e mecanismos compensatórios neuro-hormonais, acompanhada de altos índices de morbidade e mortalidade, e caracterizada por sintomas clínicos como fadiga, dispneia, e intolerância aos esforços físicos. Embora a IC seja uma síndrome de origem cardíaca, observam-se
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2012
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2. Impact of beta-2 Thr164lle and combined beta-adrenergic receptor polymorphisms on prognosis in a cohort of heart failure outpatients
Genetic polymorphisms of adrenergic receptors (ARs) have been associated with the development, progression, and prognosis of patients with heart failure (HF), with few data for the Brazilian population. We evaluated the role of the β2-AR Thr164Ile polymorphism at codon 164 on prognosis in a prospective study on 315 adult Brazilian HF patients, predominantly
Publicado em: 2011
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3. Papel dos canais K+ATP na resposta eletrofisiológica ao FSH e ao isoproterenol em células de Sertoli
Follicle-stimulating hormone (FSH) produces a dual effect on the membrane potential of Sertoli cells, with an initial rapid phase, which comprises a hyperpolarization for a period of seconds and a depolarization phase, wich occurs more slowly, within minutes. The depolarization phase involves calcium entry stimulated by FSH. Isoproterenol, an agonist of ¿-a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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4. Efeito da ingestão aguda de gordura na resposta vasodilatadora muscular em portadores de polimorfismo nos receptores B2-adrenérgicos / Effect of acute fat intake on vascular reactivity response in individuals with polymorphism in the beta2- adrenoceptors
Indivíduos portadores do glutamato na posição 27 do gene que codifica para o receptor beta2-adrenérgico têm resposta vasodilatadora muscular aumentada durante manobras fisiológicas. No entanto, o impacto do consumo agudo de gordura nessa resposta não é conhecido. Neste estudo, testou-se a hipótese de que o consumo gordura afetaria a resposta vasodil
Publicado em: 2007
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5. Associação dos polimorfismos Gln27, Glu27, Arg16 e Gly16 do gene ADRB2R com asma / Association of the polymorphisms Gln27, Glu27, Arg16 e Gly16 from ADRB2R gene with asthma
The atopic asthma is an illness with 20% of average prevalence in the Brazilian population. It?s estimated that 60% of the asthma cases are intermittent or persistent light, 25% to 30% moderate and 5% to 10% serious. The receptor beta-2-adrenergic, when activated, causes the relaxation of the aerial ways? smooth muscle. The polymorphisms Arg ->Gly 16 (46 A->
Publicado em: 2007
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6. Efeito da terapia com Beta-bloqueadores em camundongos com deleção dos receptores alpha 2A/alpha 2C adrenérgicos / Effects of b- adrenergic antagonist therapy in mice lacking a 2A/a 2C adrenergic receptors
We have recently reported that disruption for both a2A ?and a2C adrenergic receptor subtypes in mice (KO) leads to sympathetic hyperactivity with evidence of heart failure (HF) by the age of 7 months. These mice provide a model system for evaluating the efficiency among different ?- adrenergic antagonists (BB) for HF therapy. In the present study, we evaluat
Publicado em: 2006
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7. Arrythmogenesis by catecholamines in atrial and ventricular rat myocardium : methodology and types of adrenoceptors / Arritmogenese por catecolaminas em miocardio atrial e ventricular de ratos : metodologia e tipos de adrenoceptores envolvidos
Embora haja demonstração de que a estimulação simpática tenha efeito facilitatório sobre a indução de atividade espontânea em miocárdio há controvérsia sobre a participação dos tipos de adrenoceptores na mediação deste efeito. No presente trabalho, descrevemos um método desenvolvido para determinação, em átrio esquerdo isolado (AE) de rat
Publicado em: 2006
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8. Inotropic effect of Citrus sinensis (L.) Osbeck leaf extracts on the guinea pig atrium
The objective of the present investigation was to determine the contractile effect of crude and acetone leaf extracts of Citrus sinensis (L.) Osb. on mammalian myocardium. Crude leaf extracts have been used in folk medicine to treat neurological disorders. Some flavonoids isolated from this plant presented a positive inotropic effect on myocardium. This moti
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-01
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9. Estudo do efeito da dobutamina (Dobutrex) R e da radiação laser sobre a ação hidrosmotica da vasopressina em bexiga de sapo "in vitro"
In the present work the effects of several pharmacological agents in special Dobutamine and a physical agent-Laser radiation - on the events that follow the interaction of Vasopressin with membrane receptors related to syn¬thesis and inactivation of cyclic-AMP in the toad bladder, are described and characterized. Water flow across the membrane was measured
Publicado em: 1991
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10. Beta 2-adrenergic receptors contribute to catecholamine-stimulated shortening of action potential duration in dog atrial muscle.
beta 1- and beta 2-adrenergic receptors coexist in atria of humans and a variety of other species. The significance of these receptors and the quantitative extent to which beta 2-adrenergic receptors contribute to the electrophysiologic effects of catecholamines acting at beta-adrenergic receptors have not been determined. In the present study, the beta 1-se
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11. Beta 2-adrenergic receptors are colocalized and coregulated with "whisker barrels" in rat somatosensory cortex.
Autoradiography has been used to visualize independently the subtypes of beta-adrenergic receptors in rat somatosensory cortex. Beta 2-Adrenergic receptors, but not beta 1-adrenergic receptors colocalize with "whisker barrels" in this tissue. Thus, each whisker sends a specific multisynaptic pathway to the somatosensory cortex that can be histochemically vis
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12. Quantitative autoradiography of beta 1- and beta 2-adrenergic receptors in rat brain.
We have used quantitative autoradiography to localize in rat brain beta 1- and beta 2-adrenergic receptors. These receptors were labeled in vitro with 125I-labeled pindolol, an antagonist of beta-adrenergic receptors that binds nonselectively to both beta 1 and beta 2 subtypes. The selective inhibition of 125I-labeled pindolol binding with specific antagonis