Cannabinoids
Mostrando 1-12 de 65 artigos, teses e dissertações.
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1. QUANTIFICAÇÃO DE CANABINOIDES EM EXTRATOS MEDICINAIS DE Cannabis POR CROMATOGRAFIA LÍQUIDA DE ALTA EFICIÊNCIA
Cannabidiol (CBD) and tetrahydrocannabinol (THC) are the main active principles in the Cannabis extracts. Rich-CBD extracts are indicated to control seizures in epileptic patients, THC is indicated as antiemetic to patients in chemotherapy treatment and extracts with THC and CBD in proportions of approximately 1:1 are indicated to control spasticity in patie
Quím. Nova. Publicado em: 2020-01
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2. Perspectives in veterinary medicine on the use of cannabinoids as complementary palliative therapy for pain in cancer patients
RESUMO: A dor no paciente com câncer é uma manifestação clínica importante que resulta em baixa perspectiva de vida e pior prognóstico. Esta dor pode estar relacionada ao tipo de tumor, à invasão em tecidos adjacentes, metástases, procedimentos diagnósticos e terapêuticos, com resposta variável à terapêutica analgésica. Muitos estudos têm cha
Cienc. Rural. Publicado em: 28/02/2019
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3. Cirrhotic cardiomyopathy: the liver affects the heart
Cirrhotic cardiomyopathy historically has been confused as alcoholic cardiomyopathy. The key points for diagnosis of cirrhotic cardiomyopathy have been well explained, however this entity was neglected for a long time. Nowadays the diagnosis of this entity has become important because it is a factor that contributes significantly to morbidity-mortality in ci
Braz J Med Biol Res. Publicado em: 14/02/2019
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4. Analysis of Isomeric Cannabinoid Standards and Cannabis Products by UPLC-ESI-TWIM-MS: a Comparison with GC-MS and GC × GC-QMS
The Cannabis sativa L. plant has a complex chemical composition, containing various chemical compounds such as terpenes, sugars, hydrocarbons, steroids, flavonoids, and amino acids. Few works have attempted to identify the constitutional isomers of cannabinoids that are found in the plant. The present study reported the analysis of seven cannabinoid standard
J. Braz. Chem. Soc.. Publicado em: 2019-01
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5. What do Cochrane systematic reviews say about the use of cannabinoids in clinical practice?
ABSTRACT BACKGROUND: The therapeutic effects of cannabinoid compounds have been the center of many investigations. This study provides a synthesis on all Cochrane systematic reviews (SRs) that assessed the use of cannabinoids as a therapeutic approach. DESIGN AND SETTING: Review of SRs, conducted in the Discipline of Evidence-Based Medicine, Escola Pauli
Sao Paulo Med. J.. Publicado em: 22/10/2018
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6. A spider derived peptide, PnPP-19, induces central antinociception mediated by opioid and cannabinoid systems
Abstract Background Some peptides purified from the venom of the spider Phoneutria nigriventer have been identified as potential sources of drugs for pain treatment. In this study, we characterized the antinociceptive effect of the peptide PnPP-19 on the central nervous system and investigated the possible involvement of opioid and cannabinoid systems in i
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 19/01/2017
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7. Synthetic cannabinoids in the kidneys
Summary Acute kidney injury is an important cause of mortality and morbidity today and can occur due to several reasons. As time, geographic regions, and living conditions change, various etiological agents arise with nephrotoxic effects. Awareness of such nephrotoxic effects has been raised with the increasing frequency of addictive substance use, especiall
Rev. Assoc. Med. Bras.. Publicado em: 2017-01
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8. Analysis of Blotter Papers Employed in the Commercialization of New Hallucinogenic Substances of the 2,5-Dimethoxy- N-(2-methoxybenzyl) Phenethylamine Series Seized in the City of Bogotá by Applying Gas Chromatography Coupled to a Selective Mass Ion Trap Detector
In recent years, the production, distribution and consumption of so-called new psychoactive substances, such as synthetic cannabinoids, synthetic cathinones, and phenethylamines, have increased worldwide. The present work reports the identification of such substances found in samples of blotter papers that were seized in the city of Bogotá in accordance wit
J. Braz. Chem. Soc.. Publicado em: 2016-06
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9. Designer drugs: aspectos analíticos e biológicos
In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and improvement of specific and appropriate analytical methods. This work is a review of the literature which s
Química Nova. Publicado em: 2012
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10. Análise forense: pesquisa de drogas vegetais interferentes de testes colorimétricos para identificação dos canabinoides da maconha (Cannabis Sativa L.)
Marijuana (Cannabis sativa L.) is the most cultivated, trafficked and consumed illicit drug worldwide. Estimates indicate 10% of individuals experiencing marijuana become daily users, and 20-30% use it weekly. Around 489 natural compounds have been identified in this plant, of which 70 are cannabinoids, responsible for psychic effects. The most relevant cann
Quím. Nova. Publicado em: 2012
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11. Canabinoides sintéticos: drogas de abuso emergentes
CONTEXTO: A Cannabis sativa (cannabis, maconha, marijuana) é uma droga de abuso com efeitos psicoativos e potencial terapêutico bastante conhecidos. Um grande número de canabinoides foi sintetizado na tentativa de excluir ou minimizar os efeitos psicotrópicos e mantendo as aplicações terapêuticas. Os canabinoides sintéticos representam o mais recente
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2012
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12. Colite experimental induzida pelo Ãcido trinitrobenzeno sulfÃnico (TNBS) em ratos reduz a resposta hipernociceptiva inflamatÃria- papel das vias endocanabinÃides, opiÃides endÃgenos e NO/GMPC/PKG/K+ATP. / Colitis experimental induced by trinitric benzene sulfonic acid (TNBS) decreased the mechanical inflammatory hypernoception in rats - role of cannabinoids, opioids and NO/cGMP/PKG/KATP pathway.
O presente teve por objetivo avaliar a diminuiÃÃo da resposta hipernociceptiva inflamatÃria no curso do desenvolvimento da colite experimental induzida pelo Ãcido TNBS em ratos, bem como avaliar o papel da via NO/GMPc/PKG/K+ATP e a participaÃÃo de opioides endÃgenos e endocanabinoides neste evento. Para tanto, as colites foram induzidas por TNBS (20mg
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/06/2011