Carbapenem Resistance
Mostrando 1-12 de 141 artigos, teses e dissertações.
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1. Carbapenem-resistant bacilli in a hospital in southern Brazil: prevalence and therapeutic implications
Abstract Background Gram-negative bacilli (GNB), notably Acinetobacter spp., Pseudomonas spp., and Klebsiella spp., are becoming increasingly resistant to carbapenems and are associated with high health care costs and mortality, becoming a global concern. Objective To determine the prevalence rates of carbapenem resistance among Acinetobacter spp., Pseudom
Braz J Infect Dis. Publicado em: 2020-10
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2. Mobile genetic elements associated with carbapenemase genes in South American Enterobacterales
ABSTRACT Introduction: Carbapenem resistance in members of order Enterobacterales is a growing public health problem causing high mortality in developing and industrialized countries. Its emergence and rapid propagation worldwide was due to both intercontinental spread of pandemic strains and horizontal dissemination via mobile genetic elements (MGE) such a
Braz J Infect Dis. Publicado em: 2020-06
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3. Acinetobacter baumannii infections in Amazon Region driven by extensively drug resistant international clones, 2016-2018
BACKGROUND Acinetobacter baumannii is a leading cause of nosocomial infections. This species is characterised by the presence of pandemic lineages (International Clones) that present a broad antimicrobial resistance profile. OBJECTIVE To perform the molecular epidemiology of carbapenem-resistant A. baumannii from a clinical setting in the Amazon Basin, an
Mem. Inst. Oswaldo Cruz. Publicado em: 25/11/2019
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4. Emerging carbapenem-resistant Aeromonas spp. infections in Cali, Colombia
ABSTRACT Introduction: Aeromonas species are renowned enteric pathogens with virulence determinants linked to human diseases, such as gastroenteritis, skin, soft-tissue and muscle infections, and septicemia. A recent concern of resistance in this organism has emerged, especially the presence carbapenemases. Herein we describe a case series of emerging carba
Braz J Infect Dis. Publicado em: 25/11/2019
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5. High rate of detection of OXA-23-producing Acinetobacter from two general hospitals in Brazil
Abstract INTRODUCTION In recent decades, the prevalence of carbapenem-resistant Acinetobacter isolates has increased, and the production of oxacillinase (OXA)-type carbapenemases is the main mechanism underlying resistance. We evaluated OXA production from 114 Acinetobacter isolates collected between March and December 2013 from different clinical specimen
Rev. Soc. Bras. Med. Trop.. Publicado em: 05/09/2019
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6. Non-clonal occurrence of pmrB mutations associated with polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae in Brazil
BACKGROUND Polymyxins are currently used as a “last-line” treatment for multidrug-resistant Gram-negative infections. OBJECTIVES To identify the major mechanisms of resistance to polymyxin and compare the genetic similarity between multi-drug resistant Klebsiella pneumoniae strains recovered from inpatients of public hospitals in the Mid-West of Braz
Mem. Inst. Oswaldo Cruz. Publicado em: 20/05/2019
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7. Molecular epidemiology of 16S rRNA methyltransferase in Brazil: RmtG in Klebsiella aerogenes ST93 (CC4)
Abstract Aminoglycosides are a class of antibiotics that play a key role in antimicrobial treatment of Multidrug resistant (MDR) Gram-negative bacilli, typically in combination with β-lactams. Ribosomal 16S RNA modification by methyltransferases (e.g. RmtG) is an aminoglycoside resistance mechanism that, along with the occurrence carbapenem-resistant Entero
An. Acad. Bras. Ciênc.. Publicado em: 17/12/2018
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8. Prevalence of metallo-β-lactamase-encoding genes among carbapenem-resistant Pseudomonas aeruginosa strains isolated from burn patients in Iran
Abstract Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has been considered a major cause of infection and mortality in burn patients, especially in developing countries such as Iran. One of the most common mechanisms of carbapenem resistance is production of metallo-β-lactamases [(MBLs), including Verona Integron-encoded Metallo-beta-lactamase (VIM), i
Rev. Soc. Bras. Med. Trop.. Publicado em: 2018-06
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9. Epidemiology of diabetic foot infections in a reference tertiary hospital in India
Abstract Introduction The present study attempts to examine the microbial profile and antibiotic susceptibility of diabetic foot infections in the intensive care unit of a tertiary referral centre for diabetic foot. As part of the study, we also attempted to find the prevalence of blaNDM-like gene among carbapenem-resistant gram negative infections. Method
Braz. J. Microbiol.. Publicado em: 2018-06
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10. Ceftolozane-tazobactam activity against drug-resistant Enterobacteriaceae and Pseudomonas aeruginosa causing healthcare-associated infections in Latin America: report from an antimicrobial surveillance program (2013-2015)
ABSTRACT This study evaluated the in vitro activity of ceftolozane-tazobactam and comparator agents tested against Latin American isolates of Enterobacteriaceae and Pseudomonas aeruginosa from patients with health care-associated infections. Ceftolozane-tazobactam is an antipseudomonal cephalosporin combined with a well-established β-lactamase inhibitor.A t
Braz J Infect Dis. Publicado em: 2017-12
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11. Detection of multidrug-resistant Pseudomonas aeruginosa harboring bla GES-1 and bla GES-11 in Recife, Brazil
Abstract INTRODUCTION: Pseudomonas aeruginosa, an important pathogen globally, presents several resistance mechanisms. This study aimed to investigate the presence of bla GES in clinical isolates of Pseudomonas aeruginosa obtained from various clinical specimens from patients admitted to three different hospitals in Recife, Brazil. The Guiana extended spect
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-12
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12. Mobile health application to assist doctors in antibiotic prescription - an approach for antibiotic stewardship
ABSTRACT Background: Technologies applied to mobile devices can be an important strategy in antibiotic stewardship programs. Objective: The aim of this study was to determine the impact of a decision-making application on antibiotic prescription. Methods: This was an observational, analytical and longitudinal study on the implementation of an antimicrobia
Braz J Infect Dis. Publicado em: 2017-12