Cell Division
Mostrando 1-12 de 3185 artigos, teses e dissertações.
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1. The relationship between red cell distribution width and prognostic scores in myelodysplastic syndrome
ABSTRACT Introduction: The myelodysplastic syndrome (MDS) represents a group of hematopoietic neoplasms that is characterized by clonal hematopoiesis, cytopenia and abnormal cellular maturation. Red cell distribution width (RDW) refers to the variation degree of erythrocyte size and it is a reflection of anisocytosis. Higher values have been linked to adver
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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2. Effects of growth hormone in the central nervous system
ABSTRACT Growth hormone (GH) is best known for its effect stimulating tissue and somatic growth through the regulation of cell division, regeneration and proliferation. However, GH-responsive neurons are spread over the entire central nervous system, suggesting that they have important roles in the brain. The objective of the present review is to summarize a
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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3. BINARY CO-CULTURE SELECTION FROM MARINE-DERIVED MICROORGANISMS FOR DIFFERENTIAL PRODUCTION OF SPECIALIZED METABOLITES
Nowadays the discovery of new compounds from microorganisms has substantially decreased. Genomic studies have shown that certain genes are not expressed under standard laboratory conditions. In order to overcome this problem, several methods including microorganism co-culture have been developed. The aim of this work was to select binary co-cultures of marin
Quím. Nova. Publicado em: 26/08/2019
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4. Nanotechnology for the treatment of deep endometriosis: uptake of lipid core nanoparticles by LDL receptors in endometriotic foci
OBJECTIVE: Rapidly dividing cells in multiple types of cancer and inflammatory diseases undergo high low density lipoprotein (LDL) uptake for membrane synthesis, and coupling an LDL-like nanoemulsion, containing lipid nanoparticles (LDE) to a chemotherapeutic agent efficiently targets these cells without significant systemic effects. This was a prospective
Clinics. Publicado em: 10/07/2019
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5. Overexpression of CDC7 in malignant salivary gland tumors correlates with tumor differentiation
Resumo Introdução: A cell division cycle-7 é uma serina/treonina quinase que tem um papel básico na regulação do ciclo celular e é um potencial marcador prognóstico ou terapêutico em alguns tipos de câncer humano. Objetivos: Este estudo investigou a expressão de cell division cycle-7 em tumores de glândulas salivares benignos e malignos e tamb�
Braz. j. otorhinolaryngol.. Publicado em: 29/04/2019
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6. Synthesis of New 1,2,3-Triazolo-naphthalimide/phthalimide Conjugates via ‘Click' Reaction: DNA Intercalation and Cytotoxic Studies
Cancer is a complex disease which involves abnormalities of multiple cellular pathways. Current chemotherapeutic drugs are mainly designed to target the DNA and cell division. Therefore, in the present study, we have synthesized a new series of 1,2,3-triazolo-naphthalimide/phthalimide conjugates and evaluated their in vitro cytotoxicity against selected huma
J. Braz. Chem. Soc.. Publicado em: 2019-03
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7. Natural products as new antimitotic compounds for anticancer drug development
Cell cycle control genes are frequently mutated in cancer cells, which usually display higher rates of proliferation than normal cells. Dysregulated mitosis leads to genomic instability, which contributes to tumor progression and aggressiveness. Many drugs that disrupt mitosis have been studied because they induce cell cycle arrest and tumor cell death. Thes
Clinics. Publicado em: 10/12/2018
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8. Proteomic analysis of the acquired enamel pellicle formed on human and bovine tooth: a study using the Bauru in situ pellicle model (BISPM)
Abstract The acquired enamel pellicle (AEP) is an organic film, bacteria-free, formed in vivo as a result of the selective adsorption of salivary proteins and glycoproteins to the solid surfaces exposed to the oral environment. Objective: This study aimed to compare the proteomic profile of AEP formed in situ on human and bovine enamel using a new intraoral
J. Appl. Oral Sci.. Publicado em: 10/12/2018
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9. Cell Division in genus Corynebacterium: protein-protein interaction and molecular docking of SepF and FtsZ in the understanding of cytokinesis in pathogenic species
ABSTRACT The genus Corynebacterium includes species of great importance in medical, veterinary and biotechnological fields. The genus-specific families (PLfams) from PATRIC have been used to observe conserved proteins associated to all species. Our results showed a large number of conserved proteins that are associated with the cellular division process. Was
An. Acad. Bras. Ciênc.. Publicado em: 15/02/2018
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10. Morphologic study of the effect of iron on pseudocyst formation in Trichomonas vaginalis and its interaction with human epithelial cells
BACKGROUND Trichomonas vaginalis is the aetiological agent of human trichomoniasis, which is one of the most prevalent sexually transmitted diseases in humans. Iron is an important element for the survival of this parasite and the colonisation of the host urogenital tract. OBJECTIVES In this study, we investigated the effects of iron on parasite prolifera
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-10
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11. Excavation of attractor modules for nasopharyngeal carcinoma via integrating systemic module inference with attract method
The molecular mechanism of nasopharyngeal carcinoma (NPC) is poorly understood and effective therapeutic approaches are needed. This research aimed to excavate the attractor modules involved in the progression of NPC and provide further understanding of the underlying mechanism of NPC. Based on the gene expression data of NPC, two specific protein-protein in
Braz J Med Biol Res. Publicado em: 10/07/2017
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12. Telomere length correlates with disease severity and inflammation in sickle cell disease
ABSTRACT Background: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic inflammation, this study sought to determine the
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-06